منابع مشابه
Molecular abnormalities of collagen.
Many inherited abnormalities of collagen are likely and may be listed under the following headings as proved, probable, or possible. Proved Ehlers-Danlos syndrome (EDS) (types III, IV, V, VI, VII); osteogenesis imperfecta (broadboned type); thanatophoric dwarfism; dermatosparaxis (animal equivalent of EDS VII); blotchy mice (animal equivalent of EDS V). Probable Marfan syndrome; pseudoxanthoma ...
متن کاملMolecular abnormalities of collagen in human disease.
Collagen proteins are a diverse family of structural materials serving a mechanical supportive role in widely varied tissues such as skin, bone, muscle, blood vessels, cartilage, pleuroperitoneal linings, hollow tubular organs, tendons, heart valves, and basement membranes. They may also possess a crucial directive role in embryogenesis and fetal development. The molecules are large, ranging be...
متن کاملMolecular biomechanics of collagen molecules
1 Laboratory for Atomistic and Molecular Mechanics, Department of Civil and Environmental Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Room 1-290, Cambridge, MA, USA Center for Materials Science and Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA, USA Center for Computational Engineering, Massachusetts Institute of Techn...
متن کاملTaurine prevents collagen abnormalities in high fructose-fed rats.
BACKGROUND & OBJECTIVE Accumulation of collagen and changes in its physiochemical properties contribute to the development of secondary complications of diabetes. We undertook this study to see the effects of taurine on the content and characteristics of collagen from tail tendon of rats fed with high fructose diet. METHODS The rats were divided into four groups of six each: control group (CO...
متن کاملMimecan/osteoglycin-deficient mice have collagen fibril abnormalities.
PURPOSE To study the role of mimecan, a member of the small leucine-rich proteoglycans (SLRPs) gene family and one of the major components of the cornea and other connective tissues, mice that lack a functional mimecan gene were generated and characterized. METHODS Mimecan-deficient mice were generated by gene-targeting using standard techniques. Mice were genotyped by Southern blot analysis....
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ژورنال
عنوان ژورنال: Journal of Clinical Pathology
سال: 1978
ISSN: 0021-9746
DOI: 10.1136/jcp.s3-12.1.95